Oxandrolone (also known under the trade names Anavar, Oksandrin, Vasorome, Anatrofill et al.) – Anabolic steroid created by Searle Laboratories, and released under the trade mark Anavar in 1964.
Oxandrolone is a synthetic steroid, which ring A is a heterocycle, wherein the second carbon atom is substituted with an oxygen atom. Oxandrolone is widely known because of its extremely low level of androgenic activity along with high anabolic index.
Has the highest among the immunostimulatory effect of steroids, significantly increases the sensitivity of tissues to insulin. Initially, oxandrolone has been developed for the treatment of debilitated HIV-infected patients with osteoporosis, osteochondrosis, Turner syndrome, anemia, to speed up recovery after burns, prolonged bed rest, in type II diabetes associated with obesity. Soon he began to actively use in bodybuilding, then Anavar was listed as a controlled substance.
The steroid profile
- Anabolic activity – 400% of testosterone
- Androgenic activity – 25% of testosterone
- Aromatization (conversion to estrogen) – No
- Toxicity to the liver – moderate / weak
- A method of receiving – by mouth (tablets)
- The half-life – 8-12 hours
- Detection time – up to 60 days
The effects of oxandrolone
- Increasing the hardness of muscles and relief – the main effect of oxandrolone
- fat Burning
- Increasing the level of growth hormone
- Increased strength
Anavar is inappropriate to use for a set of muscle mass. Anavar course is recommended for people who have sufficient muscle and a moderate fat content in the body to give relief of muscles and fat reduction.
Oxandrolone for burning fat
Scientists from the University of Southern California conducted an experiment , which showed that the harvested adipose tissue is not returned immediately after the cancellation of the steroid.
The study was sponsored by the US government and manufacturer of oxandrolone – Savient. In the experiment, which lasted 12 weeks, men took part, does not take lifting weights older than 60 years.
The study found that men not only get rid of fat, but also gained some muscle mass in 12 weeks, even without strength training. The daily dosage of the steroid was 20 mg, adipose tissue loss was 1.8 kg. However, over the next 12 weeks to gain muscle mass is gone, but the effect of fat loss is preserved. It returned only 17% of adipose tissue. Furthermore, it was found that the major changes in body composition occurred during the first 6 weeks. Therefore they tend to short courses of oxandrolone, as the most effective.
- The loss of adipose tissue in cm2
- Fat on the abdomen 25
- Subcutaneous fat 10
- Fat on hips 8
- Fat on lap 3
- Intermuscular fat tissue of the body 8
- Intermuscular fat tissue of extremities 2
Researchers concluded that oxandrolone is more effective drug for fat loss than for a set of muscle mass. But do not forget that the loss of 2 kg of fat tissue in 12 weeks is easily achievable without taking AAS.
The study also found that fat loss as increased sensitivity to insulin. That is, the body was able to do less of this hormone in response to the receipt of food substrates into the blood, and thus the risk of conversion of glucose into fat decreased.
Side effects of oxandrolone
Despite the fact that oxandrolone is an alpha-17-alkylated steroid of its toxic effect on the liver slightly. Studies show that Anavar 20 mg per day, taken for 12 weeks did not affect the level of liver enzymes (liver failure indicators). The first signs of liver damage is a pain in the right upper quadrant, light stools and dark urine.
Since Anavar is a derivative of dihydrotestosterone, it does not aromatize (not converted into estrogen, which cause side effects such as gynecomastia and fluid accumulation in the body).
Oxandrolone has no significant effect on the level of natural testosterone production in moderate doses (does not inhibit the hypothalamic-pituitary-testes feedback mechanism axis). When the dosage of Anavar is high, the body reacts to a decrease in gonadotropin production, suggesting that endogenous testosterone level is too high. Lack of stimulation of Leydig cells leads to testicular atrophy. Oxandrolone is used in a dose of 80 mg per day suppresses testosterone levels after 12 weeks of 67%
Suppression of testosterone production appears sluggish decline in libido and erectile dysfunction. Fix the side-effect of oxandrolone possible by the addition of gonadotropin in the course or conduct courses combined with androgen drugs.
Also, sometimes there are side effects of Anavar as loss of appetite, abdominal pain, nausea, headaches, rise in blood pressure and others.
In general, the side effects of oxandrolone are rare, Anavar is one of the safest steroids.
- As mentioned above, the course of Anavar “solo” is held to enhance muscle relief. The total duration of 6-8 weeks.
- Check out the general principles of construction of a course of steroids in the article – the best courses of steroids.
- Start taking oxandrolone at a dose of 20 mg per day, divided into two stages – in the morning and early afternoon.
- One week Anavar increase the dosage to 40, a maximum of 80 mg per day, divided into 3 doses.
- Continue the course with no side effects for 5-6 weeks.
- After 2 days after the end of Anavar begin tamoxifen at a dose of 10 mg per day to restore natural testosterone for 1-2 weeks.
- oxandrolone course requires prior consultation of a doctor to identify contraindications (prostate hypertrophy, liver disease, etc.).
- To maximize the effectiveness of the course, take sports nutrition for relief
Combined courses of oxandrolone
In order to prevent some of the side effects of oxandrolone (decreased libido, erection sluggish, toxic effects on the liver) and the accompanying side effects of drugs, and also to get great results, it is recommended to include in the course of Anavar vysokoandrogennye drugs:
We must also take into account:
- When combined with other drugs, dosage of oxandrolone it is typically about 40 mg per day.
- Combined courses will not only get relief, but also to increase muscle mass.
To maximize the effectiveness of the complex of sports nutrition for muscle mass set and follow a diet for a set of muscle mass.